A Fundamentally Different Approach

Unique innovations unlock simplicity, low cost, and high performance

Clear partitions allow for rapid 3D scanning

Analysis of 30+ million partitions on UltraPCR is simple. UltraPCR leverages a proprietary emulsion chemistry that is thermally stable and optically clear such that we can directly image the PCR tube using 3D imaging.

UltraPCR

Others

  • Single-tube workflow from partitioning to analysis eliminates risks of cross-sample contamination.

  • UltraPCR Imager can scan 30+ million partitions in under a minute per channel.

  • Immobilized emulsions combined with serial imaging creates "optical signature" profiles of each positive partition, enabling more fluorescent dyes to be used on the UltraPCR system.

UltraPartitioning™

Efficient partitioning without microfluidics with no dead volume

  • Centrifugation-based partitioning using a standard benchtop centrifuge

  • 30+ million partitions per sample directly placed into PCR tubes, 1000X+ more partitions than conventional dPCR

  • Industry-leading 50 uL PCR reactions with no dead volume

Singlet Counting™

Counting DNA the way it should be - 1 molecule at a time.

Singlet partitions in UltraPCR

Mixed molecule partitions in dPCR

  • 30+million partitions enables >1 million molecules, each in its own “singlet” partition

  • Count with simplicity and confidence - 1 positive singlet partition equals 1 DNA molecule

  • Eliminate the need of Poisson statistics arising from limited partitions in legacy dPCR systems

  • True single molecule counting over an unmatched 6-log dynamic range, achieving the true concept of digital PCR

UltraClear 3D™

Clarity in 3D provides direct peek of singlet partitions directly from PCR tubes.

Ultra-dPCR

Other dPCR

  • Proprietary chemistry enables formation of thermally stable and optically clear partitions for rapid, high-resolution 3D scanning in the same tube

  • Positive partitions are counted directly from within the PCR tube, providing a streamlined, single-tube workflow and eliminating risks of cross-sample contaminations

  • UltraPCR platform uses lightsheet imaging to provide high resolution 3D microscopy directly in PCR tubes with clear partitions

  • UltraClear 3D can scan 34 million partitions in under a minute per channel

Universal Multiplex™

Bringing multiplexing for everyday use.

  • Novel multiplexing alternative using a standard pair of PCR primers without the need of expensive hydrolysis probes

  • Rapid, low cost, multiplexed panel design (up to 4 with standard product offering)

  • Comparable counting performance as hydrolysis probes

Comboplex™

COMING SOON

Unprecedented level of multiplexing unlocked in UltraPCR.