A Fundamentally Different Approach

Unique innovations unlock simplicity, low cost, and high performance

Rapid 3D scanning of individual molecules

Countable PCR leverages a proprietary matrix chemistry that is thermally stable and optically clear, enabling direct 3D imaging of the PCR reaction.

Countable PCR

Others

  • Single-tube workflow from partitioning to analysis eliminates risks of cross-sample contamination.

  • The Countable system scans up to 1 million single molecules in under a minute per channel

  • Direct imaging of the sample preparation enables creation of an “optical signature” for each positive partition, enabling the use of more fluorescent dyes within the same reaction for better multiplexing capabilities

UltraPartitioning™

Efficient partitioning without microfluidics with no dead volume

  • Centrifugation-based partitioning using a standard benchtop centrifuge

  • 30+ million partitions per sample directly placed into PCR tubes, 1000X+ more partitions than conventional dPCR

  • Industry-leading 50 uL PCR reactions with no dead volume

Singlet Counting™

Counting DNA the way it should be - 1 molecule at a time.

Singlet partitions in UltraPCR

Mixed molecule partitions in dPCR

  • 30+million partitions enables >1 million molecules, each in its own “singlet” partition

  • Count with simplicity and confidence - 1 positive singlet partition equals 1 DNA molecule

  • Eliminate the need of Poisson statistics arising from limited partitions in legacy dPCR systems

  • True single molecule counting over an unmatched 6-log dynamic range, achieving the true concept of digital PCR

UltraClear 3D™

Clarity in 3D provides direct peek of singlet partitions directly from PCR tubes.

Ultra-dPCR

Other dPCR

  • Proprietary chemistry enables formation of thermally stable and optically clear partitions for rapid, high-resolution 3D scanning in the same tube

  • Positive partitions are counted directly from within the PCR tube, providing a streamlined, single-tube workflow and eliminating risks of cross-sample contaminations

  • UltraPCR platform uses lightsheet imaging to provide high resolution 3D microscopy directly in PCR tubes with clear partitions

  • UltraClear 3D can scan 34 million partitions in under a minute per channel

Universal Multiplex™

Bringing multiplexing for everyday use.

  • Novel multiplexing alternative using a standard pair of PCR primers without the need of expensive hydrolysis probes

  • Rapid, low cost, multiplexed panel design (up to 4 with standard product offering)

  • Comparable counting performance as hydrolysis probes

Comboplex™

COMING SOON

Unprecedented level of multiplexing unlocked in UltraPCR.